Possible re-infection with unvaccinated COVID-19 virus

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Charlotte, Nick (StudyFinds.org) – Since the beginning of the epidemic, scientists, doctors, and everyone in between have wondered how long strong immunity lasts after recovering from a SARS infection.

Now, researchers from Yale University and the University of North Carolina at Charlotte have some sad news. They report strong protection from COVID-19 after recovery that does not last long.

“Re-infection can reasonably occur in three months or less,” explains lead study author Jeffrey Townsend, Elihu Professor of Biostatistics at the Yale School of Public Health. University release. “Therefore, those who have been infected naturally He must be vaccinated. Previous infection alone can provide very little long-term protection against subsequent infection.”

The study authors reached these imperfect conclusions by analyzing re-infection and immunological data collected from close viral relatives of SARS-CoV-2 that causes the “common cold.”

It also included immunological datasets from both SARS-CoV-1 and Middle East Respiratory Syndrome (MERS). By taking advantage of evolutionary principles, the researchers believe they have been able to accurately model the risk of re-infection with COVID-19 over time.

Variants of COVID-19 increase the risk of reinfection

While re-infection among those who have already recovered from COVID-19 is already fairly common, the research team warns that such events are likely to become more common. As more variants emerge.

“We tend to think of immunity as immunity or not immunity. Our study warns that instead we should be more focused risk of injury again Through time,” explains study co-leader Alex Dornberg, associate professor of bioinformatics and genomics at the University of North Carolina in Charlotte. As new variants emerge, previous immune responses become less effective in fighting the virus. Those who were naturally infected early in the pandemic They are increasingly likely to become infected in the near future.”

According to research, the risk of reinfection associated with COVID-19 is very similar to that of endemic coronaviruses.

“exactly like ColdsFrom year to year, you may get the same virus again. The difference is that during its emergence in this pandemic, COVID-19 has proven to be much more deadly.” Adds Professor Townsend.

“Given the ability of SARS-CoV-2 to evolve and re-infect, it is also more likely to move from pandemic to endemic,” notes Professor Dornberg.

“The hallmark of the modern world will be Evolution of new threats on human health,” concludes Professor Townsend. “Evolutionary biology – which provided the theoretical underpinnings for these analyzes – is traditionally considered a historical discipline. Nonetheless, our findings underscore its important role in informing decision-making, and provide an important stepping stone towards a solid knowledge of our prospects for resistance to SARS-CoV-2 re-infection.”

The the findings appeared in Lancet microbe.

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